MAIN KEGG FILE RESULTS

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName	#Gene	EntrezGene	Statistics
Spliceosome	4	6625 24148 56259 26121	C=127;O=4;E=0.25;R=15.98;rawP=0.0001;adjP=0.0009
Metabolic pathways	8	5432 83549 7108 9374 3633 10423 30815 126328	C=1130;O=8;E=2.23;R=3.59;rawP=0.0018;adjP=0.0081
Inositol phosphate metabolism	2	3633 10423	C=57;O=2;E=0.11;R=17.80;rawP=0.0057;adjP=0.0171
Adipocytokine signaling pathway	2	6794 6257	C=68;O=2;E=0.13;R=14.92;rawP=0.0080;adjP=0.0180
Phosphatidylinositol signaling system	2	3633 10423	C=78;O=2;E=0.15;R=13.01;rawP=0.0105;adjP=0.0189
Pyrimidine metabolism	2	5432 83549	C=99;O=2;E=0.20;R=10.25;rawP=0.0165;adjP=0.0248
Huntington's disease	2	5432 126328	C=183;O=2;E=0.36;R=5.55;rawP=0.0508;adjP=0.0653
Regulation of actin cytoskeleton	2	54961 10458	C=213;O=2;E=0.42;R=4.76;rawP=0.0664;adjP=0.0747
Pathways in cancer	2	4254 6257	C=326;O=2;E=0.64;R=3.11;rawP=0.1355;adjP=0.1355

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).